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Echinobase

Summary Expression Gene Literature (40) GO Terms (57) Nucleotides (27) Proteins (23) Interactants (109) Wiki
ECB-GENEPAGE-23150120
???displayGene.symbol??? :
 otx2
Symbol Status : Partially Curated


???displayGene.name???: 
orthodenticle homeobox 2
Name Status : Partially Curated


???displayGene.synonyms???
LOC110974187 , orthodenticle homolog , otx , Sp-Otx , SPU_010424 [-] ( Nomenclature history )

???displayGene.geneFunction???
May play a role in activation of the SPEC2A gene, binds to the TAATCC motif with high specificity. May have additional functions in the developing embryos. Subunit: Binds DNA as a monomer. Developmental Stage: Found initially in all cells of the cleaving embryo, but gradually becomes restricted to oral ectoderm and endoderm cells.

AI Protein Function :
The otx2 gene in Strongylocentrotus purpuratus encodes a homeodomain transcription factor that functions in anterior patterning, specifically in the development of the anterior neuroectoderm and ectode...[+]


???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
microphthalmia [+]

MIM:
MICROPHTHALMIA, SYNDROMIC 5; MCOPS5 [+]

External Links:
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