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Echinobase

Summary ExpressionExpr. Gene Literature (0)Lit. (0) GO Terms (107)GO (107) Nucleotides (10)Nucl. (10) Proteins (7)Prot. (7) Interactants (10)Interact. (10) Wiki
ECB-GENEPAGE-23078986
???displayGene.symbol??? :
 eif2ak3
Symbol Status : Curated


???displayGene.name???: 
eukaryotic translation initiation factor 2 alpha kinase 3
Name Status : Curated


???displayGene.synonyms???
eukaryotic translation initiation factor 2-alpha kinase , Eukaryotic translation initiation factor 2-alpha kinase 3 precursor , LOC110983394 , LOC587307 , Sp-Eif2ak3perk , SPU_026724 [+] ( Nomenclature history )

AI Protein Function :
eif2ak3 encodes a serine/threonine‑protein kinase that acts as a signaling molecule in the unfolded protein response by phosphorylating eIF2α to modulate translation initiation, participates in endopla...[+]


InterPro :
Protein kinase ATP BS, Ser/Thr kinase AS, Kinase-like dom sf, Prot kinase dom, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
Wolcott-Rallison syndrome

MIM:
EPIPHYSEAL DYSPLASIA, MULTIPLE, WITH EARLY-ONSET DIABETES MELLITUS

External Links:
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