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ECB-GENEPAGE-23049519
???displayGene.symbol???
:
h2a
Symbol Status
:
Partially Curated
???displayGene.name???
:
histone h2A
Name Status
:
Partially Curated
???displayGene.synonyms???
EhH2a
,
EhH2a_1
,
EhH2a_10
,
EhH2a_11
,
EhH2a_12
,
EhH2a_13
[+]
(
Nomenclature history )
???displayGene.geneFunction???
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the
AI Protein Function
:
The h2a gene encodes a histone H2A protein that functions in nucleosome assembly and chromatin organization, involved in DNA packaging within the nucleus.
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