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ECB-GENEPAGE-23049519
???displayGene.symbol??? : h2a
Symbol Status
:
Partially Curated
???displayGene.name???: histone h2A
Name Status
:
Partially Curated
???displayGene.synonyms???
EhH2a
,
EhH2a_1
,
EhH2a_10
,
EhH2a_11
,
EhH2a_12
,
EhH2a_13
[+]
(
???displayGene.geneFunction??? Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the Protein Function :
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central ro...[+]
???displayGene.geneInteractants???
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Diseases: External Links:
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Symbol legend: Blast sequence View sequence Literature or expression images Hover cursor for info