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Summary Expression Gene Literature (25) GO Terms (0) Nucleotides (12) Proteins (4) Interactants (117) Wiki
ECB-GENEPAGE-23157746

Papers associated with cdk2



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Cyclin A potentiates maturation-promoting factor activation in the early Xenopus embryo via inhibition of the tyrosine kinase that phosphorylates cdc2., Devault A, Fesquet D, Cavadore JC, Garrigues AM, Labbé JC, Lorca T, Picard A, Philippe M, Dorée M., J Cell Biol. September 1, 1992; 118 (5): 1109-20.


The MO15 gene encodes the catalytic subunit of a protein kinase that activates cdc2 and other cyclin-dependent kinases (CDKs) through phosphorylation of Thr161 and its homologues., Fesquet D, Labbé JC, Derancourt J, Capony JP, Galas S, Girard F, Lorca T, Shuttleworth J, Dorée M, Cavadore JC., EMBO J. August 1, 1993; 12 (8): 3111-21.


Purification of a 15-kDa cdk4- and cdk5-binding protein., Azzi L, Meijer L, Ostvold AC, Lew J, Wang JH., J Biol Chem. May 6, 1994; 269 (18): 13279-88.


Cellular effects of olomoucine, an inhibitor of cyclin-dependent kinases., Abraham RT, Acquarone M, Andersen A, Asensi A, Bellé R, Berger F, Bergounioux C, Brunn G, Buquet-Fagot C, Fagot D., Biol Cell. January 1, 1995; 83 (2-3): 105-20.


MAT1 (''menage à trois'') a new RING finger protein subunit stabilizing cyclin H-cdk7 complexes in starfish and Xenopus CAK., Devault A, Martinez AM, Fesquet D, Labbé JC, Morin N, Tassan JP, Nigg EA, Cavadore JC, Dorée M., EMBO J. October 16, 1995; 14 (20): 5027-36.


Newly assembled cyclin B-cdc2 kinase is required to suppress DNA replication between meiosis I and meiosis II in starfish oocytes., Picard A, Galas S, Peaucellier G, Dorée M., EMBO J. July 15, 1996; 15 (14): 3590-8.


Inhibition of cyclin-dependent kinases by purine analogues: crystal structure of human cdk2 complexed with roscovitine., De Azevedo WF, Leclerc S, Meijer L, Havlicek L, Strnad M, Kim SH., Eur J Biochem. January 15, 1997; 243 (1-2): 518-26.


Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5., Meijer L, Borgne A, Mulner O, Chong JP, Blow JJ, Inagaki N, Inagaki M, Delcros JG, Moulinoux JP., Eur J Biochem. January 15, 1997; 243 (1-2): 527-36.


Cdk2 activity is dispensable for the onset of DNA replication during the first mitotic cycles of the sea urchin early embryo., Moreau JL, Marques F, Barakat A, Schatt P, Lozano JC, Peaucellier G, Picard A, Genevière AM., Dev Biol. August 15, 1998; 200 (2): 182-97.


Synthesis and in vitro evaluation of novel 2,6,9-trisubstituted purines acting as cyclin-dependent kinase inhibitors., Legraverend M, Ludwig O, Bisagni E, Leclerc S, Meijer L, Giocanti N, Sadri R, Favaudon V., Bioorg Med Chem. July 1, 1999; 7 (7): 1281-93.


Characterization of a novel cdk1-related kinase., Détivaud L, Pettit GR, Meijer L., Eur J Biochem. August 1, 1999; 264 (1): 55-66.


Cyclin E and its associated cdk activity do not cycle during early embryogenesis of the sea Urchin., Sumerel JL, Moore JC, Schnackenberg BJ, Nichols JA, Canman JC, Wessel GM, Marzluff WF., Dev Biol. June 15, 2001; 234 (2): 425-40.


Novel localization and possible functions of cyclin E in early sea urchin development., Schnackenberg BJ, Marzluff WF., J Cell Sci. January 1, 2002; 115 (Pt 1): 113-21.


Molecular cloning and characterisation of p15(CDK-BP), a novel CDK-binding protein., Vogel L, Baratte B, Détivaud L, Azzi L, Leopold P, Meijer L., Biochim Biophys Acta. April 3, 2002; 1589 (2): 219-31.


Drosophila cyclin E interacts with components of the Brahma complex., Brumby AM, Zraly CB, Horsfield JA, Secombe J, Saint R, Dingwall AK, Richardson H., EMBO J. July 1, 2002; 21 (13): 3377-89.


Roscovitine and other purines as kinase inhibitors. From starfish oocytes to clinical trials., Meijer L, Raymond E., Acc Chem Res. June 1, 2003; 36 (6): 417-25.


Calyculin A causes the activation of histone H1 kinase and condensation of chromosomes in unfertilized sea urchin eggs independently of the maturation-promoting factor., Tosuji H, Fusetani N, Seki Y., Comp Biochem Physiol C Toxicol Pharmacol. August 1, 2003; 135 (4): 415-24.


N2-substituted O6-cyclohexylmethylguanine derivatives: potent inhibitors of cyclin-dependent kinases 1 and 2., Hardcastle IR, Arris CE, Bentley J, Boyle FT, Chen Y, Curtin NJ, Endicott JA, Gibson AE, Golding BT, Griffin RJ, Jewsbury P, Menyerol J, Mesguiche V, Newell DR, Noble ME, Pratt DJ, Wang LZ, Whitfield HJ., J Med Chem. July 15, 2004; 47 (15): 3710-22.


A genetic screen for dominant modifiers of a cyclin E hypomorphic mutation identifies novel regulators of S-phase entry in Drosophila., Brumby A, Secombe J, Horsfield J, Coombe M, Amin N, Coates D, Saint R, Richardson H., Genetics. September 1, 2004; 168 (1): 227-51.


Homology model of the CDK1/cyclin B complex., McGrath CF, Pattabiraman N, Kellogg GE, Lemcke T, Kunick C, Sausville EA, Zaharevitz DW, Gussio R., J Biomol Struct Dyn. April 1, 2005; 22 (5): 493-502.


Cyclin E/Cdk2 is required for sperm maturation, but not DNA replication, in early sea urchin embryos., Schnackenberg BJ, Palazzo RE, Marzluff WF., Genesis. May 1, 2007; 45 (5): 282-91.


Cyclin E in centrosome duplication and reduplication in sea urchin zygotes., Schnackenberg BJ, Marzluff WF, Sluder G., J Cell Physiol. December 1, 2008; 217 (3): 626-31.


MAP kinase dependent cyclinE/cdk2 activity promotes DNA replication in early sea urchin embryos., Kisielewska J, Philipova R, Huang JY, Whitaker M., Dev Biol. October 15, 2009; 334 (2): 383-94.              


Replication origins are already licensed in G1 arrested unfertilized sea urchin eggs., Aze A, Fayet C, Lapasset L, Genevière AM., Dev Biol. April 15, 2010; 340 (2): 557-70.


Fungal Immunomodulatory Protein from Nectria haematococca Suppresses Growth of Human Lung Adenocarcinoma by Inhibiting the PI3K/Akt Pathway., Xie Y, Li S, Sun L, Liu S, Wang F, Wen B, Sun L, Fang X, Chai Y, Cao H, Jia N, Gu T, Lou X, Xin F., Int J Mol Sci. November 1, 2018; 19 (11):             

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