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Summary Expression Gene Literature (40) GO Terms (0) Nucleotides (18) Proteins (7) Interactants (74) Wiki
ECB-GENEPAGE-23093017

Papers associated with bax



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Asterosaponin 1, a cytostatic compound from the starfish Culcita novaeguineae, functions by inducing apoptosis in human glioblastoma U87MG cells., Cheng G, Zhang X, Tang HF, Zhang Y, Zhang XH, Cao WD, Gao DK, Wang XL, Jin BQ., J Neurooncol. September 1, 2006; 79 (3): 235-41.

Homeopathic medicines do not alter growth and gene expression in prostate and breast cancer cells in vitro., Thangapazham RL, Gaddipati JP, Rajeshkumar NV, Sharma A, Singh AK, Ives JA, Maheshwari RK, Jonas WB., Integr Cancer Ther. December 1, 2006; 5 (4): 356-61.

Review of the apoptosis pathways in pancreatic cancer and the anti-apoptotic effects of the novel sea cucumber compound, Frondoside A., Li X, Roginsky AB, Ding XZ, Woodward C, Collin P, Newman RA, Bell RH, Adrian TE., Ann N Y Acad Sci. September 1, 2008; 1138 181-98.

The anti-tumor activities of cerebrosides derived from sea cucumber Acaudina molpadioides and starfish Asterias amurensis in vitro and in vivo., Du L, Li ZJ, Xu J, Wang JF, Xue Y, Xue CH, Takahashi K, Wang YM., J Oleo Sci. January 1, 2012; 61 (6): 321-30.

Steroidal constituents from the starfish Astropecten polyacanthus and their anticancer effects., Thao NP, Cuong NX, Luyen BT, Nam NH, Cuong PV, Thanh NV, Nhiem NX, Hanh TT, Kim EJ, Kang HK, Kiem PV, Minh CV, Kim YH., Chem Pharm Bull (Tokyo). January 1, 2013; 61 (10): 1044-51.

Sphingoid bases from sea cucumber induce apoptosis in human hepatoma HepG2 cells through p-AKT and DR5., Hossain Z, Sugawara T, Hirata T., Oncol Rep. March 1, 2013; 29 (3): 1201-7.

Anticancer activity and mediation of apoptosis in human HL-60 leukaemia cells by edible sea cucumber (Holothuria edulis) extract., Wijesinghe WA, Jeon YJ, Ramasamy P, Wahid ME, Vairappan CS., Food Chem. August 15, 2013; 139 (1-4): 326-31.

The protective effect of eicosapentaenoic acid-enriched phospholipids from sea cucumber Cucumaria frondosa on oxidative stress in PC12 cells and SAMP8 mice., Wu FJ, Xue Y, Liu XF, Xue CH, Wang JF, Du L, Takahashi K, Wang YM., Neurochem Int. January 1, 2014; 64 9-17.

Cytotoxic and apoptosis-inducing activity of triterpene glycosides from Holothuria scabra and Cucumaria frondosa against HepG2 cells., Wang J, Han H, Chen X, Yi Y, Sun H., Mar Drugs. July 24, 2014; 12 (8): 4274-90.            

The Potential of Brittle Star Extracted Polysaccharide in Promoting Apoptosis via Intrinsic Signaling Pathway., Baharara J, Amini E., Avicenna J Med Biotechnol. January 1, 2015; 7 (4): 151-8.              

Sigma 1 Receptor antagonist potentiates the anti-cancer effect of p53 by regulating ER stress, ROS production, Bax levels, and caspase-3 activation., Happy M, Dejoie J, Zajac CK, Cortez B, Chakraborty K, Aderemi J, Sauane M., Biochem Biophys Res Commun. January 9, 2015; 456 (2): 683-8.

Putative mechanism for apoptosis-inducing properties of crude saponin isolated from sea cucumber (Holothuria leucospilota) as an antioxidant compound., Soltani M, Parivar K, Baharara J, Kerachian MA, Asili J., Iran J Basic Med Sci. February 1, 2015; 18 (2): 180-7.              

Plancitoxin I from the venom of crown-of-thorns starfish (Acanthaster planci) induces oxidative and endoplasmic reticulum stress associated cytotoxicity in A375.S2 cells., Lee CC, Hsieh HJ, Hsieh CH, Hwang DF., Exp Mol Pathol. August 1, 2015; 99 (1): 7-15.

Molecular effects of the phosphatidylinositol-3-kinase inhibitor NVP-BKM120 on T and B-cell acute lymphoblastic leukaemia., Pereira JK, Machado-Neto JA, Lopes MR, Morini BC, Traina F, Costa FF, Saad ST, Favaro P., Eur J Cancer. September 1, 2015; 51 (14): 2076-85.

Sulfated Polysaccharide Isolated from the Sea Cucumber Stichopus japonicus Against PC12 Hypoxia/Reoxygenation Injury by Inhibition of the MAPK Signaling Pathway., Cui C, Cui N, Wang P, Song S, Liang H, Ji A., Cell Mol Neurobiol. November 1, 2015; 35 (8): 1081-92.

Evaluation of the Anti-proliferative Effects of Ophiocoma erinaceus Methanol Extract Against Human Cervical Cancer Cells., Baharara J, Amini E, Namvar F., Avicenna J Med Biotechnol. January 1, 2016; 8 (1): 29-35.              

Scabraside D Extracted from Holothuria scabra Induces Apoptosis and Inhibits Growth of Human Cholangiocarcinoma Xenografts in Mice., Assawasuparerk K, Vanichviriyakit R, Chotwiwatthanakun C, Nobsathian S, Rawangchue T, Wittayachumnankul B., Asian Pac J Cancer Prev. January 1, 2016; 17 (2): 511-7.

Neuroprotective effect of sulfated polysaccharide isolated from sea cucumber Stichopus japonicus on 6-OHDA-induced death in SH-SY5Y through inhibition of MAPK and NF-κB and activation of PI3K/Akt signaling pathways., Cui C, Cui N, Wang P, Song S, Liang H, Ji A., Biochem Biophys Res Commun. February 5, 2016; 470 (2): 375-383.

Fucoidan from Acaudina molpadioides protects pancreatic islet against cell apoptosis via inhibition of inflammation in type 2 diabetic mice., Wang J, Hu S, Wang J, Li S, Jiang W., Food Sci Biotechnol. February 29, 2016; 25 (1): 293-300.

Fermented Asterina pectinifera with Cordyceps militaris Mycelia Induced Apoptosis in B16F10 Melanoma Cells., Kim YS, Kim EK, Hwang JW, Kim JS, Kim H, Dong X, Natarajan SB, Moon SH, Jeon BT, Park PJ., Adv Exp Med Biol. January 1, 2017; 975 Pt 2 1141-1152.

The marine triterpene glycoside frondoside A induces p53-independent apoptosis and inhibits autophagy in urothelial carcinoma cells., Dyshlovoy SA, Madanchi R, Hauschild J, Otte K, Alsdorf WH, Schumacher U, Kalinin VI, Silchenko AS, Avilov SA, Honecker F, Stonik VA, Bokemeyer C, von Amsberg G., BMC Cancer. February 1, 2017; 17 (1): 93.            

Cerebrosides from Sea Cucumber Protect Against Oxidative Stress in SAMP8 Mice and PC12 Cells., Che H, Du L, Cong P, Tao S, Ding N, Wu F, Xue C, Xu J, Wang Y., J Med Food. April 1, 2017; 20 (4): 392-402.

Ultraviolet-Ray-Induced Sea Cucumber (Stichopus japonicus) Melting Is Mediated by the Caspase-Dependent Mitochondrial Apoptotic Pathway., Su L, Yang JF, Fu X, Dong L, Zhou DY, Sun LM, Gong Z., J Agric Food Chem. January 10, 2018; 66 (1): 45-52.

Holotoxin A₁ Induces Apoptosis by Activating Acid Sphingomyelinase and Neutral Sphingomyelinase in K562 and Human Primary Leukemia Cells., Yun SH, Sim EH, Han SH, Han JY, Kim SH, Silchenko AS, Stonik VA, Park JI., Mar Drugs. April 10, 2018; 16 (4):           

[The roles of holothurian glycosaminoglycan combined with cisplatin on proliferation and chemotherapeutic response in A549 human lung adenocarcinoma cell]., Jin Q, Zhu XH, Lin CZ, Zhang H, Cao YW, Ding XQ, Lyu ZH., Zhonghua Zhong Liu Za Zhi. April 23, 2018; 40 (4): 252-257.

Protective effects of sea cucumber (Holothuria atra) extract on testicular dysfunction induced by immune suppressant drugs in Wistar rats., Saad DY, Soliman MM, Mohamed AA, Youssef GB., Andrologia. August 1, 2018; 50 (6): e13017.

Calein C, a Sesquiterpene Lactone Isolated From Calea Pinnatifida (Asteraceae), Inhibits Mitotic Progression and Induces Apoptosis in MCF-7 Cells., Caldas LA, Horvath RO, Ferreira-Silva GÁ, Ferreira MJP, Ionta M, Sartorelli P., Front Pharmacol. October 4, 2018; 9 1191.        

In Vitro Anticancer and Proapoptotic Activities of Steroidal Glycosides from the Starfish Anthenea aspera., Malyarenko TV, Malyarenko OS, Kicha AA, Ivanchina NV, Kalinovsky AI, Dmitrenok PS, Ermakova SP, Stonik VA., Mar Drugs. November 1, 2018; 16 (11):       

Fungal Immunomodulatory Protein from Nectria haematococca Suppresses Growth of Human Lung Adenocarcinoma by Inhibiting the PI3K/Akt Pathway., Xie Y, Li S, Sun L, Liu S, Wang F, Wen B, Sun L, Fang X, Chai Y, Cao H, Jia N, Gu T, Lou X, Xin F., Int J Mol Sci. November 1, 2018; 19 (11):             

In Vivo genotoxicity of a commercial C.I. Disperse Red 1 dye., Fernandes FH, Botasso-Nasciutti MO, Svio ALV, Souza LDCM, Fernandes-Cal JR, Cardoso FF, Fontes MRM, Albuquerque AF, Munari CC, Kummrow F, Umbuzeiro GA, Salvadori DMF., Environ Mol Mutagen. December 1, 2018; 59 (9): 822-828.

The p53 Modulated Cytotoxicity of Ophiocoma scolopendrina Polysaccharide Against Resistance Ovarian Cancer Cells., Amini E, Baharara J, Afzali M, Nikdel N., Avicenna J Med Biotechnol. January 1, 2019; 11 (3): 208-214.              

Cerebrosides from Sea Cucumber Improved Aβ1-42 -Induced Cognitive Deficiency in a Rat Model of Alzheimer''s Disease., Li Q, Che HX, Wang CC, Zhang LY, Ding L, Xue CH, Zhang TT, Wang YM., Mol Nutr Food Res. March 1, 2019; 63 (5): e1800707.

In vitro and in vivo Induction of p53-Dependent Apoptosis by Extract of Euryale ferox Salisb in A549 Human Caucasian Lung Carcinoma Cancer Cells Is Mediated Through Akt Signaling Pathway., Nam GH, Jo KJ, Park YS, Kawk HW, Kim SY, Kim YM., Front Oncol. May 22, 2019; 9 406.            

Therapeutic Cell Protective Role of Histochrome under Oxidative Stress in Human Cardiac Progenitor Cells., Park JH, Lee NK, Lim HJ, Mazumder S, Kumar Rethineswaran V, Kim YJ, Jang WB, Ji ST, Kang S, Kim DY, Van LTH, Giang LTT, Kim DH, Ha JS, Yun J, Kim H, Han J, Mishchenko NP, Fedoreyev SA, Vasileva EA, Kwon SM, Baek SH., Mar Drugs. June 21, 2019; 17 (6):             

Echinochrome A Attenuates Cerebral Ischemic Injury through Regulation of Cell Survival after Middle Cerebral Artery Occlusion in Rat., Kim R, Hur D, Kim HK, Han J, Mishchenko NP, Fedoreyev SA, Stonik VA, Chang W., Mar Drugs. August 28, 2019; 17 (9):       

Effects of Polar Steroids from the Starfish Patiria (=Asterina) pectinifera in Combination with X-Ray Radiation on Colony Formation and Apoptosis Induction of Human Colorectal Carcinoma Cells., Malyarenko OS, Malyarenko TV, Kicha AA, Ivanchina NV, Ermakova SP., Molecules. August 29, 2019; 24 (17):         

Bax functions as coelomocyte apoptosis regulator in the sea cucumber Apostichopus japonicus., Guo M, Lv M, Shao Y, Zhang W, Zhao X, Li C., Dev Comp Immunol. January 1, 2020; 102 103490.

A sea cucumber (Holothuria leucospilota) polysaccharide improves the gut microbiome to alleviate the symptoms of type 2 diabetes mellitus in Goto-Kakizaki rats., Zhao F, Liu Q, Cao J, Xu Y, Pei Z, Fan H, Yuan Y, Shen X, Li C., Food Chem Toxicol. January 1, 2020; 135 110886.

Effects of Holothurian Glycosaminoglycan on the Sensitivity of Lung Cancer to Chemotherapy., Lin C, Zhu X, Jin Q, Sui A, Li J, Shen L., Integr Cancer Ther. January 1, 2020; 19 1534735420911430.          

MYC regulates coelomocytes apoptosis by targeting Bax expression in sea cucumber Apostichopus japonicus., Zhang Y, Shao Y, Lv Z, Li C., Fish Shellfish Immunol. February 1, 2020; 97 27-33.

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