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Summary Expression Gene Literature (40) GO Terms (3) Nucleotides (32) Proteins (20) Interactants (109) Wiki

Papers associated with otx2

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Coup-TF: A maternal factor essential for differentiation along the embryonic axes in the sea urchin Paracentrotus lividus., Tsironis I, Paganos P, Gouvi G, Tsimpos P, Stamopoulou A, Arnone MI, Flytzanis CN., Dev Biol. July 1, 2021; 475 131-144.

Early asymmetric cues triggering the dorsal/ventral gene regulatory network of the sea urchin embryo., Cavalieri V, Spinelli G., Elife. December 2, 2014; 3 e04664.                            

Molecular conservation of metazoan gut formation: evidence from expression of endomesoderm genes in Capitella teleta (Annelida)., Boyle MJ, Yamaguchi E, Seaver EC., Evodevo. June 17, 2014; 5 39.          

How Hox genes can shed light on the place of echinoderms among the deuterostomes., David B, Mooi R., Evodevo. June 17, 2014; 5 22.              

The Compass-like locus, exclusive to the Ambulacrarians, encodes a chromatin insulator binding protein in the sea urchin embryo., Cavalieri V, Melfi R, Spinelli G., PLoS Genet. January 1, 2013; 9 (9): e1003847.        

Gene expression analysis of Six3, Pax6, and Otx in the early development of the stalked crinoid Metacrinus rotundus., Omori A, Akasaka K, Kurokawa D, Amemiya S., Gene Expr Patterns. January 1, 2011; 11 (1-2): 48-56.

Ancestral regulatory circuits governing ectoderm patterning downstream of Nodal and BMP2/4 revealed by gene regulatory network analysis in an echinoderm., Saudemont A, Haillot E, Mekpoh F, Bessodes N, Quirin M, Lapraz F, Duboc V, Röttinger E, Range R, Oisel A, Besnardeau L, Wincker P, Lepage T., PLoS Genet. December 23, 2010; 6 (12): e1001259.                      

Characterization and expression of a sea star otx ortholog (Protxβ1/2) in the larva of Patiriella regularis., Elia L, Cisternas P, Byrne M., Gene Expr Patterns. January 1, 2010; 10 (7-8): 323-7.

Monte Carlo analysis of an ODE Model of the Sea Urchin Endomesoderm Network., Kühn C, Wierling C, Kühn A, Klipp E, Panopoulou G, Lehrach H, Poustka AJ., BMC Syst Biol. August 23, 2009; 3 83.                      

cis-Regulatory sequences driving the expression of the Hbox12 homeobox-containing gene in the presumptive aboral ectoderm territory of the Paracentrotus lividus sea urchin embryo., Cavalieri V, Di Bernardo M, Anello L, Spinelli G., Dev Biol. September 15, 2008; 321 (2): 455-69.

A spatially dynamic cohort of regulatory genes in the endomesodermal gene network of the sea urchin embryo., Smith J, Kraemer E, Liu H, Theodoris C, Davidson E., Dev Biol. January 15, 2008; 313 (2): 863-75.

Caught in the evolutionary act: precise cis-regulatory basis of difference in the organization of gene networks of sea stars and sea urchins., Hinman VF, Nguyen A, Davidson EH., Dev Biol. December 15, 2007; 312 (2): 584-95.

DNA variations within the sea urchin Otx gene enhancer., Yamamoto T, Kawamoto R, Fujii T, Sakamoto N, Shibata T., FEBS Lett. November 13, 2007; 581 (27): 5234-40.

A gene regulatory network subcircuit drives a dynamic pattern of gene expression., Smith J, Theodoris C, Davidson EH., Science. November 2, 2007; 318 (5851): 794-7.

Sequential logic model deciphers dynamic transcriptional control of gene expressions., Yeo ZX, Wong ST, Arjunan SN, Piras V, Tomita M, Selvarajoo K, Giuliani A, Tsuchiya M., PLoS One. August 22, 2007; 2 (8): e776.                  

Regulation of spblimp1/krox1a, an alternatively transcribed isoform expressed in midgut and hindgut of the sea urchin gastrula., Livi CB, Davidson EH., Gene Expr Patterns. January 1, 2007; 7 (1-2): 1-7.

Real-time monitoring of functional interactions between upstream and core promoter sequences in living cells of sea urchin embryos., Kobayashi A, Watanabe Y, Akasaka K, Kokubo T., Nucleic Acids Res. January 1, 2007; 35 (14): 4882-94.                

Repression of mesodermal fate by foxa, a key endoderm regulator of the sea urchin embryo., Oliveri P, Walton KD, Davidson EH, McClay DR., Development. November 1, 2006; 133 (21): 4173-81.

Involvement of two Hox genes and Otx in echinoderm body-plan morphogenesis in the sea urchin Holopneustes purpurescens., Morris VB, Byrne M., J Exp Zool B Mol Dev Evol. September 15, 2005; 304 (5): 456-67.

Strongylocentrotus purpuratus transcription factor GATA-E binds to and represses transcription at an Otx-Goosecoid cis-regulatory element within the aboral ectoderm-specific spec2a enhancer., Kiyama T, Zhang N, Dayal S, Yun Lee P, Liang S, Villinski JT, Klein WH., Dev Biol. April 15, 2005; 280 (2): 436-47.

A genetic regulatory network for Xenopus mesendoderm formation., Loose M, Patient R., Dev Biol. July 15, 2004; 271 (2): 467-78.

An otx cis-regulatory module: a key node in the sea urchin endomesoderm gene regulatory network., Yuh CH, Dorman ER, Howard ML, Davidson EH., Dev Biol. May 15, 2004; 269 (2): 536-51.

Expression of an Otx gene in the adult rudiment and the developing central nervous system in the vestibula larva of the sea urchin Holopneustes purpurescens., Morris VB, Zhao JT, Shearman DC, Byrne M, Frommer M., Int J Dev Biol. February 1, 2004; 48 (1): 17-22.

The Otx binding site is required for the activation of HpOtxL mRNA expression in the sea urchin, Hemicentrotus pulcherrimus., Hayashibara Y, Mitsunaga-Nakatsubo K, Sakamoto N, Shimotori T, Akasaka K, Yamamoto T., Dev Growth Differ. February 1, 2004; 46 (1): 61-7.

Expression and function of a starfish Otx ortholog, AmOtx: a conserved role for Otx proteins in endoderm development that predates divergence of the eleutherozoa., Hinman VF, Nguyen AT, Davidson EH., Mech Dev. October 1, 2003; 120 (10): 1165-76.

Evolutionary convergence in Otx expression in the pentameral adult rudiment in direct-developing sea urchins., Nielsen MG, Popodi E, Minsuk S, Raff RA., Dev Genes Evol. March 1, 2003; 213 (2): 73-82.

Functional interaction between TATA and upstream CACGTG elements regulates the temporally specific expression of Otx mRNAs during early embryogenesis of the sea urchin, Hemicentrotus pulcherrimus., Kobayashi A, Akasaka K, Kawaichi M, Kokubo T., Nucleic Acids Res. July 15, 2002; 30 (14): 3034-44.

Patchy interspecific sequence similarities efficiently identify positive cis-regulatory elements in the sea urchin., Yuh CH, Brown CT, Livi CB, Rowen L, Clarke PJ, Davidson EH., Dev Biol. June 1, 2002; 246 (1): 148-61.

A regulatory gene network that directs micromere specification in the sea urchin embryo., Oliveri P, Carrick DM, Davidson EH., Dev Biol. June 1, 2002; 246 (1): 209-28.

Gene expression and larval evolution: changing roles of distal-less and orthodenticle in echinoderm larvae., Lowe CJ, Issel-Tarver L, Wray GA., Evol Dev. January 1, 2002; 4 (2): 111-23.

Correct Expression of spec2a in the sea urchin embryo requires both Otx and other cis-regulatory elements., Yuh CH, Li X, Davidson EH, Klein WH., Dev Biol. April 15, 2001; 232 (2): 424-38.

CAAT sites are required for the activation of the H. pulcherrimus Ars gene by Otx., Kiyama T, Sasai K, Takata K, Mitsunaga-Nakatsubo K, Shimada H, Akasaka K., Dev Genes Evol. December 1, 2000; 210 (12): 583-90.

Expression of the otx gene in the ciliary bands during sea cucumber embryogenesis., Shoguchi E, Harada Y, Numakunai T, Satoh N., Genesis. June 1, 2000; 27 (2): 58-63.

Function and evolution of Otx proteins., Klein WH, Li X., Biochem Biophys Res Commun. May 10, 1999; 258 (2): 229-33.

Differential expression of sea urchin Otx isoform (hpOtxE and HpOtxL) mRNAs during early development., Mitsunaga-Nakatsubo K, Akasaka K, Sakamoto N, Takata K, Matsumura Y, Kitajima T, Kusunoki S, Shimada H., Int J Dev Biol. July 1, 1998; 42 (5): 645-51.

Two Otx proteins generated from multiple transcripts of a single gene in Strongylocentrotus purpuratus., Li X, Chuang CK, Mao CA, Angerer LM, Klein WH., Dev Biol. July 15, 1997; 187 (2): 253-66.

Two isoforms of orthodenticle-related proteins (HpOtx) bind to the enhancer element of sea urchin arylsulfatase gene., Sakamoto N, Akasaka K, Mitsunaga-Nakatsubo K, Takata K, Nishitani T, Shimada H., Dev Biol. January 15, 1997; 181 (2): 284-95.

Transient appearance of Strongylocentrotus purpuratus Otx in micromere nuclei: cytoplasmic retention of SpOtx possibly mediated through an alpha-actinin interaction., Chuang CK, Wikramanayake AH, Mao CA, Li X, Klein WH., Dev Genet. January 1, 1996; 19 (3): 231-7.

Characterization of the SpHE promoter that is spatially regulated along the animal-vegetal axis of the sea urchin embryo., Wei Z, Angerer LM, Gagnon ML, Angerer RC., Dev Biol. September 1, 1995; 171 (1): 195-211.

Multiple Otx binding sites required for expression of the Strongylocentrotus purpuratus Spec2a gene., Mao CA, Gan L, Klein WH., Dev Biol. September 1, 1994; 165 (1): 229-42.

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