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Summary Expression Gene Literature (29) GO Terms (5) Nucleotides (3) Proteins (3) Interactants (80) Wiki
ECB-GENEPAGE-23147089

Papers associated with LOC582192



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Frondoside A Enhances the Anti-Cancer Effects of Oxaliplatin and 5-Fluorouracil on Colon Cancer Cells., Attoub S, Arafat K, Khalaf T, Sulaiman S, Iratni R., Nutrients. 10 (5):   


A sea cucumber (Holothuria leucospilota) polysaccharide improves the gut microbiome to alleviate the symptoms of type 2 diabetes mellitus in Goto-Kakizaki rats., Zhao F, Liu Q, Cao J, Xu Y, Pei Z, Fan H, Yuan Y, Shen X, Li C., Food Chem Toxicol. January 1, 2020; 135 110886.

Glycosaminoglycan from Apostichopus japonicus Improves Glucose Metabolism in the Liver of Insulin Resistant Mice., Chen Y, Wang Y, Yang S, Yu M, Jiang T, Lv Z., Mar Drugs. December 18, 2019; 18 (1):   


SGK regulates pH increase and cyclin B-Cdk1 activation to resume meiosis in starfish ovarian oocytes., Hosoda E, Hiraoka D, Hirohashi N, Omi S, Kishimoto T, Chiba K., J Cell Biol. November 4, 2019; 218 (11): 3612-3629.   


Glycosaminoglycan from Apostichopus japonicus inhibits hepatic glucose production via activating Akt/FoxO1 and inhibiting PKA/CREB signaling pathways in insulin resistant hepatocytes., Chen Y, Liu H, Wang Y, Yang S, Yu M, Jiang T, Lv Z., Food Funct. November 1, 2019; 10 (11): 7565-7575.

Echinochrome A Attenuates Cerebral Ischemic Injury through Regulation of Cell Survival after Middle Cerebral Artery Occlusion in Rat., Kim R, Hur D, Kim HK, Han J, Mishchenko NP, Fedoreyev SA, Stonik VA, Chang W., Mar Drugs. August 28, 2019; 17 (9):   


Cerebrosides from Sea Cucumber Improved Aβ1-42 -Induced Cognitive Deficiency in a Rat Model of Alzheimer''s Disease., Li Q, Che HX, Wang CC, Zhang LY, Ding L, Xue CH, Zhang TT, Wang YM., Mol Nutr Food Res. March 1, 2019; 63 (5): e1800707.

Comparative toxicity evaluation of targeted anticancer therapeutics in embryonic zebrafish and sea urchin models., Babic T, Dinic J, Buric SS, Hadzic S, Pesic M, Radojkovic D, Rankov AD., Acta Biol Hung. December 1, 2018; 69 (4): 395-410.

MPF-based meiotic cell cycle control: Half a century of lessons from starfish oocytes., Kishimoto T., Proc Jpn Acad Ser B Phys Biol Sci. January 1, 2018; 94 (4): 180-203.   


Frondoside A from sea cucumber and nymphaeols from Okinawa propolis: Natural anti-cancer agents that selectively inhibit PAK1 in vitro., Nguyen BCQ, Yoshimura K, Kumazawa S, Tawata S, Maruta H., Drug Discov Ther. May 30, 2017; 11 (2): 110-114.

Stichopus japonicus Polysaccharide, Fucoidan, or Heparin Enhanced the SDF-1α/CXCR4 Axis and Promoted NSC Migration via Activation of the PI3K/Akt/FOXO3a Signaling Pathway., Cui C, Wang P, Cui N, Song S, Liang H, Ji A., Cell Mol Neurobiol. November 17, 2016; 36 (8): 1311-1329.

Two new competing pathways establish the threshold for cyclin-B-Cdk1 activation at the meiotic G2/M transition., Hiraoka D, Aono R, Hanada S, Okumura E, Kishimoto T., J Cell Sci. August 15, 2016; 129 (16): 3153-66.   


Sulfated polysaccharide isolated from the sea cucumber Stichopus japonicas promotes the SDF-1α/CXCR4 axis-induced NSC migration via the PI3K/Akt/FOXO3a, ERK/MAPK, and NF-κB signaling pathways., Cui C, Wang P, Cui N, Song S, Liang H, Ji A., Neurosci Lett. March 11, 2016; 616 57-64.

Neuroprotective effect of sulfated polysaccharide isolated from sea cucumber Stichopus japonicus on 6-OHDA-induced death in SH-SY5Y through inhibition of MAPK and NF-κB and activation of PI3K/Akt signaling pathways., Cui C, Cui N, Wang P, Song S, Liang H, Ji A., Biochem Biophys Res Commun. February 5, 2016; 470 (2): 375-383.

Structure-Activity Relationship Study of the Neuritogenic Potential of the Glycan of Starfish Ganglioside LLG-3 (‡)., Yamagishi M, Hosoda-Yabe R, Tamai H, Konishi M, Imamura A, Ishida H, Yabe T, Ando H, Kiso M., Mar Drugs. December 5, 2015; 13 (12): 7250-74.   


Anticancer activity of sea cucumber triterpene glycosides., Aminin DL, Menchinskaya ES, Pisliagin EA, Silchenko AS, Avilov SA, Kalinin VI., Mar Drugs. March 6, 2015; 13 (3): 1202-23.   


Asterosaponins from the Starfish Astropecten monacanthus suppress growth and induce apoptosis in HL-60, PC-3, and SNU-C5 human cancer cell lines., Thao NP, Luyen BT, Kim EJ, Kang HK, Kim S, Cuong NX, Nam NH, Kiem PV, Minh CV, Kim YH., Biol Pharm Bull. January 1, 2014; 37 (2): 315-21.

Nitrosative/oxidative stress conditions regulate thioredoxin-interacting protein (TXNIP) expression and thioredoxin-1 (TRX-1) nuclear localization., Ogata FT, Batista WL, Sartori A, Gesteira TF, Masutani H, Arai RJ, Yodoi J, Stern A, Monteiro HP., PLoS One. December 16, 2013; 8 (12): e84588.   


Sea urchin akt activity is Runx-dependent and required for post-cleavage stage cell division., Robertson AJ, Coluccio A, Jensen S, Rydlizky K, Coffman JA., Biol Open. March 25, 2013; 2 (5): 472-8.   


Sphingoid bases from sea cucumber induce apoptosis in human hepatoma HepG2 cells through p-AKT and DR5., Hossain Z, Sugawara T, Hirata T., Oncol Rep. March 1, 2013; 29 (3): 1201-7.

Turn motif phosphorylation negatively regulates activation loop phosphorylation in Akt., Hiraoka D, Okumura E, Kishimoto T., Oncogene. November 3, 2011; 30 (44): 4487-97.

A polysaccharide from Strongylocentrotus nudus eggs protects against myelosuppression and immunosuppression in cyclophosphamide-treated mice., Wang H, Wang M, Chen J, Tang Y, Dou J, Yu J, Xi T, Zhou C., Int Immunopharmacol. November 1, 2011; 11 (11): 1946-53.

Sulfated polysaccharide isolated from the sea cucumber Stichopus japonicus promotes neurosphere migration and differentiation via up-regulation of N-cadherin., Sheng X, Li M, Song S, Zhang N, Wang Y, Liang H, Wang W, Ji A., Cell Mol Neurobiol. April 23, 2011; 32 (3): 435-42.

A primer on meiotic resumption in starfish oocytes: the proposed signaling pathway triggered by maturation-inducing hormone., Kishimoto T., Mol Reprod Dev. January 1, 2011; 78 (10-11): 704-7.

Hormone-induced cortical maturation ensures the slow block to polyspermy and does not couple with meiotic maturation in starfish., Hirohashi N, Harada K, Chiba K., Dev Biol. June 1, 2008; 318 (1): 194-202.

PKB/AKT is involved in resumption of meiosis in mouse oocytes., Kalous J, Solc P, Baran V, Kubelka M, Schultz RM, Motlik J., Biol Cell. February 1, 2006; 98 (2): 111-23.

PE, a new sulfated saponin from sea cucumber, exhibits anti-angiogenic and anti-tumor activities in vitro and in vivo., Tian F, Zhang X, Tong Y, Yi Y, Zhang S, Li L, Sun P, Lin L, Ding J., Cancer Biol Ther. August 1, 2005; 4 (8): 874-82.

PDK1 is required for the hormonal signaling pathway leading to meiotic resumption in starfish oocytes., Hiraoka D, Hori-Oshima S, Fukuhara T, Tachibana K, Okumura E, Kishimoto T., Dev Biol. December 15, 2004; 276 (2): 330-6.

Akt inhibits Myt1 in the signalling pathway that leads to meiotic G2/M-phase transition., Okumura E, Fukuhara T, Yoshida H, Hanada Si S, Kozutsumi R, Mori M, Tachibana K, Kishimoto T., Nat Cell Biol. February 1, 2002; 4 (2): 111-6.

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