Changhu Xue - Publications

Publications (131)

ECB-PERS-4179

Publications By Changhu Xue

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Serum metabolomics analysis reveals amelioration effects of sea cucumber ether phospholipids on oxidative stress and inflammation in high-fat diet-fed mice., Wang X, Lan H, Sun T, Cong P, Xue C, Xu J., Food Funct. 13 (19): 10134-10146.
Fucoidan from sea cucumber cooking liquid: Structural analysis, physicochemical properties, and anti-Helicobacter pylori potential., Cao J, Qin L, Liu M, Yao M, Wang K, Lin H, Qu C, He Y, Xue C, Miao J., Int J Biol Macromol. February 28, 2025; 141593.
A novel endo-1,3-fucanase in glycoside hydrolase family 187 provided a biotechnological tool for preparing sulfated fucan oligosaccharides., Shen J, Zheng L, Chen G, Khamleng A, Xue C, Chang Y., Int J Biol Macromol. February 16, 2025; 305 (Pt 2): 141171.
Establishment of a workflow for high-throughput identification of anti-inflammatory peptides from sea cucumbers., Jiang B, Liu J, Zhu Z, Fu L, Chang Y, Wang Y, Xue C., Food Res Int. December 29, 2024; 197 (Pt 1): 115171.
Biochemical characterization and cleavage specificities analyses of three endo-1,3-fucanases within glycoside hydrolase family 174., Shen J, Liu G, Chen G, Zhang Y, Mei X, Zheng L, Xue C, Chang Y., Carbohydr Polym. July 1, 2024; 335 122083.
Investigation of the Presence of Fibrillin in Sea Cucumber (Apostichopus japonicus) Body Wall by Utilizing Targeted Proteomics and Visualization Strategies., Shi F, Liu K, Chen G, Chang Y, Xue C., J Agric Food Chem. April 17, 2024; 72 (15): 8798-8804.
Sea Cucumber Plasmalogen Regulates the Lipid Profile in High-Fat Diet Mouse Liver via Lipophagy., Wang Z, Wang X, Liu Y, Wang X, Meng N, Cong P, Song Y, Xu J, Xue C., J Agric Food Chem. April 17, 2024;
Sea cucumber plasmalogen enhance lipophagy to alleviate abnormal lipid accumulation induced by high-fat diet., Wang Z, Liu Y, Wang X, Wang X, Wu Y, Song Y, Xu J, Xue C., Biochim Biophys Acta Mol Cell Biol Lipids. April 10, 2024; 1869 (5): 159495.
Novel peptides from sea cucumber intestines hydrolyzed by neutral protease alleviate exercise-induced fatigue via upregulating the glutaminemediated Ca2+ /Calcineurin signaling pathway in mice., Lu X, Wang M, Yue H, Feng X, Tian Y, Xue C, Zhang T, Wang Y., J Food Sci. March 1, 2024; 89 (3): 1727-1738.
The cross-linking ability of dialdo-galactose in food processing condition., Liu Y, Yu J, Cao H, Xue C, Chen K, Xu Y, Sun X., Food Chem. February 1, 2024; 433 137356.
Establishment of a targeted proteomics method for the quantification of collagen chain: Revealing the chain stoichiometry of heterotypic collagen fibrils in sea cucumber., Shi F, Wang Y, Chang Y, Liu K, Xue C., Food Chem. February 1, 2024; 433 137335.
Preparation of Novel Sea Cucumber Intestinal Peptides to Promote Tibial Fracture Healing in Mice by Inducing Differentiation of Hypertrophic Chondrocytes to the Osteoblast Lineage., Yin H, Yue H, Wang M, Zhang T, Zhao YT, Liu H, Wang J, Zheng H, Xue C., Mol Nutr Food Res. January 1, 2024; 68 (2): e2300344.
Characterization of a novel endo-1,3-fucanase from marine bacterium Wenyingzhuangia fucanilytica reveals the presence of diversity within glycoside hydrolase family 168., Shen J, Chen G, Zhang Y, Mei X, Chang Y, Xue C., Carbohydr Polym. October 15, 2023; 318 121104.
Sulfated fucan could serve as a species marker of sea cucumber with endo-1,3-fucanase as the essential tool., Chen G, Shen J, Zhang Y, Shi F, Mei X, Xue C, Chang Y., Carbohydr Polym. July 15, 2023; 312 120817.
The synergistic effect of sea cucumber saponins and caffeine on preventing obesity in high-fat diet-fed mice by extending the action duration of caffeine., Zhao YC, Li LP, Li XY, Wang CC, Yang JY, Xue CH, Wang YM, Zhang TT., J Sci Food Agric. June 1, 2023; 103 (8): 3950-3960.
Sea Cucumber Phospholipids Regulate Cholesterol Metabolism in High-Fat Diet-Induced ApoE-/- Mice., Yang S, Wang X, Li H, Wang X, Song Y, Cong P, Xu J, Xue C., J Nutr. June 1, 2023; 153 (6): 1762-1770.
Comprehensive Lipid Profile of Eight Echinoderm Species by RPLC-Triple TOF-MS/MS., Hu X, Cong P, Song Y, Wang X, Zhang H, Meng N, Fan X, Xu J, Xue C., J Agric Food Chem. May 31, 2023; 71 (21): 8230-8240.
Novel Peptides from Sea Cucumber Intestinal Enzyme Hydrolysates Promote Osteogenic Differentiation of Bone Mesenchymal Stem Cells via Phosphorylation of PPARγ at Serine 112., Yue H, Leng Z, Bo Y, Tian Y, Yan Z, Xue C, Dong P, Wang J., Mol Nutr Food Res. May 1, 2023; 67 (9): e2200451.
Characterization of an endo-1,3-fucanase from marine bacterium Wenyingzhuangia aestuarii: The first member of a novel glycoside hydrolase family GH174., Liu G, Shen J, Chang Y, Mei X, Chen G, Zhang Y, Xue C., Carbohydr Polym. April 15, 2023; 306 120591.
Oxidized inositol stabilizes rehydrated sea cucumbers against non-enzymatic deterioration., Cao H, Liu D, Zhi L, Liu J, Liu Y, Xu H, Wang D, Xu Y, Xue C, Sun X., Food Chem. March 30, 2023; 405 (Pt B): 134973.
Investigating the loss of major yolk proteins during the processing of sea cucumber (Apostichopus japonicus) using an MRM-based targeted proteomics strategy., Jiang B, Zhang H, Wang J, Wang Y, Du X, Chang Y, Xue C., Food Chem. March 15, 2023; 404 (Pt B): 134670.
Preparation and properties of fucoxanthin-loaded liposomes stabilized by sea cucumber derived cholesterol sulfate instead of cholesterol., Wang Y, Yang J, Wang Y, Chang Y, Xue C, Zhang T., J Biosci Bioeng. February 1, 2023; 135 (2): 160-166.
Sea Cucumber Saponins Derivatives Alleviate Hepatic Lipid Accumulation Effectively in Fatty Acids-Induced HepG2 Cells and Orotic Acid-Induced Rats., Li X, Zeng B, Wen L, Zhao Y, Li Z, Xue C, Zhang T, Wang Y., Mar Drugs. November 10, 2022; 20 (11):
Novel Peptides Derived from Sea Cucumber Intestine Promotes Osteogenesis by Upregulating Integrin-Mediated Transdifferentiation of Growth Plate Chondrocytes to Osteoblasts., Yue H, Tian Y, Feng X, Bo Y, Xue C, Dong P, Wang J., J Agric Food Chem. October 19, 2022; 70 (41): 13212-13222.
A Comparative Study of the Anti-Obesity Effects of Dietary Sea Cucumber Saponins and Energy Restriction in Response to Weight Loss and Weight Regain in Mice., Wen L, Li R, Zhao YC, Yang JY, Li XY, Xue CH, Zhang TT, Wang YM., Mar Drugs. October 1, 2022; 20 (10):
Novel peptides from sea cucumber intestinal hydrolysates promote longitudinal bone growth in adolescent mice through accelerating cell cycle progress by regulating glutamine metabolism., Yue H, Tian Y, Feng X, Bo Y, Leng Z, Dong P, Xue C, Wang J., Food Funct. July 18, 2022; 13 (14): 7730-7739.
Comparative study of holothurin A and echinoside A on inhibiting the high bone turnover via downregulating PI3K/AKT/β-catenin and OPG/RANKL/NF-κB signaling in ovariectomized mice., Yue H, Tian Y, Li Y, Bai X, Wang X, Wang Y, Li Z, Xue C, Wang J., Food Funct. April 20, 2022; 13 (8): 4748-4756.
Hepatoprotective effects of sea cucumber ether-phospholipids against alcohol-induced lipid metabolic dysregulation and oxidative stress in mice., Wang X, Wang Y, Liu Y, Cong P, Xu J, Xue C., Food Funct. March 7, 2022; 13 (5): 2791-2804.
Preparation and Characterization of Astaxanthin-loaded Liposomes Stabilized by Sea Cucumber Sulfated Sterols Instead of Cholesterol., Srihera N, Li Y, Zhang TT, Wang YM, Yanagita T, Waiprib Y, Xue CH., J Oleo Sci. March 2, 2022; 71 (3): 401-410.
Characterization of a sulfated fucan-specific carbohydrate-binding module: A promising tool for investigating sulfated fucans., Mei X, Chang Y, Shen J, Zhang Y, Chen G, Liu Y, Xue C., Carbohydr Polym. February 1, 2022; 277 118748.
Absorption, Pharmacokinetics, Tissue Distribution, and Excretion Profiles of Sea Cucumber-Derived Sulfated Sterols in Mice., Li Y, Wang T, Shi HH, Wang YM, Xue CH, Huang QR, Zhang TT., J Agric Food Chem. January 19, 2022; 70 (2): 480-487.
Utilizing heterologously overexpressed endo-1,3-fucanase to investigate the structure of sulfated fucan from sea cucumber (Holothuria hilla)., Chen G, Yu L, Zhang Y, Chang Y, Liu Y, Shen J, Xue C., Carbohydr Polym. November 15, 2021; 272 118480.
Saponins from the Sea Cucumber Promote the Osteoblast Differentiation in MC3T3-E1 Cells through the Activation of the BMP2/ Smads Pathway., Li Z, Tian Y, Ma H, Wang M, Yan Z, Xue C, Wang J., Curr Pharm Biotechnol. October 6, 2021; 22 (14): 1942-1952.
Lipidomics Approach in High-Fat-Diet-Induced Atherosclerosis Dyslipidemia Hamsters: Alleviation Using Ether-Phospholipids in Sea Urchin., Wang X, Chen Q, Wang X, Cong P, Xu J, Xue C., J Agric Food Chem. August 18, 2021; 69 (32): 9167-9177.
Dietary Supplementation with Exogenous Sea-Cucumber-Derived Ceramides and Glucosylceramides Alleviates Insulin Resistance in High-Fructose-Diet-Fed Rats by Upregulating the IRS/PI3K/Akt Signaling Pathway., Yang JY, Zhang TT, Dong Z, Shi HH, Xu J, Mao XZ, Wang YM, Xue CH., J Agric Food Chem. August 18, 2021; 69 (32): 9178-9187.
Characterizing gangliosides in six sea cucumber species by HILIC-ESI-MS/MS., Wang X, Wang X, Cong P, Zhang X, Zhang H, Xue C, Xu J., Food Chem. August 1, 2021; 352 129379.
Characterization of Gangliosides in Three Sea Urchin Species by HILIC-ESI-MS/MS., Ma Y, Wang X, Wang Z, Cong P, Xu J, Xue C., J Agric Food Chem. July 14, 2021; 69 (27): 7641-7651.
Sterol sulfate alleviates atherosclerosis via mediating hepatic cholesterol metabolism in ApoE-/- mice., Ding L, Xu ZJ, Shi HH, Xue CH, Huang QR, Yanagita T, Wang YM, Zhang TT., Food Funct. June 8, 2021; 12 (11): 4887-4896.
Amino Acid Profiling with Chemometric Analysis as a Feasible Tool for the Discrimination of Marine-Derived Peptide Powders., Wang Q, Wang Y, Jiang X, Ma L, Li Z, Chang Y, Wang Y, Xue C., Foods. June 4, 2021; 10 (6):
Uncovering proteome variations of differently heat-treated sea cucumber (Apostichopus japonicus) by label-free mass spectrometry., Jiang B, Hu L, Zhang X, Zhang H, Zhang F, Chen L, Li Z, Zhao X, Xue C, Jiang X., Food Chem. May 15, 2021; 344 128575.
Sea urchin gangliosides exhibit neuritogenic effects in neuronal PC12 cells via TrkA- and TrkB-related pathways., Wang X, Li Y, Wang Y, Liu Y, Xue C, Cong P, Xu J., Biosci Biotechnol Biochem. February 24, 2021; 85 (3): 675-686.
Structure-function relationship analysis of fucoidan from sea cucumber (Holothuria tubulosa) on ameliorating metabolic inflammation., Zhu Y, Tian Y, Wang N, Chang Y, Xue C, Wang J., J Food Biochem. January 1, 2021; 45 (1): e13500.
Maternal diet with sea urchin gangliosides promotes neurodevelopment of young offspring via enhancing NGF and BDNF expression., Wang X, Cong P, Wang X, Liu Y, Wu L, Li H, Xue C, Xu J., Food Funct. November 18, 2020; 11 (11): 9912-9923.
Functional properties of gonad protein isolates from three species of sea urchin: a comparative study., Shang WH, Yan JN, Du YN, Cui XF, Su SY, Han JR, Xu YS, Xue CF, Zhang TT, Wu HT, Zhu BW., J Food Sci. November 1, 2020; 85 (11): 3679-3689.
Investigation of structural proteins in sea cucumber (Apostichopus japonicus) body wall., Wang Y, Tian M, Chang Y, Xue C, Li Z., Sci Rep. October 30, 2020; 10 (1): 18744.
Sea cucumbers-derived sterol sulfate alleviates insulin resistance and inflammation in high-fat-high-fructose diet-induced obese mice., Zhang HJ, Chen C, Ding L, Shi HH, Wang CC, Xue CH, Zhang TT, Wang YM., Pharmacol Res. October 1, 2020; 160 105191.
Exogenous natural EPA-enriched phosphatidylcholine and phosphatidylethanolamine ameliorate lipid accumulation and insulin resistance via activation of PPARα/γ in mice., Tian Y, Liu Y, Xue C, Wang J, Wang Y, Xu J, Li Z., Food Funct. September 23, 2020; 11 (9): 8248-8258.
Sea Cucumber Sterol Alleviates the Lipid Accumulation in High-Fat-Fructose Diet Fed Mice., Zeng BB, Zhang LY, Chen C, Zhang TT, Xue CH, Yanagita T, Li ZJ, Wang YM., J Agric Food Chem. September 9, 2020; 68 (36): 9707-9717.
Oxidized Oligosaccharides Stabilize Rehydrated Sea Cucumbers against High-Temperature Impact., Liu J, Xu Y, Xia T, Xue C, Liu L, Chang P, Wang D, Sun X., Int J Mol Sci. July 23, 2020; 21 (15):
The exogenous natural phospholipids, EPA-PC and EPA-PE, contribute to ameliorate inflammation and promote macrophage polarization., Tian Y, Liu Y, Xue C, Wang J, Wang Y, Xu J, Li Z., Food Funct. July 1, 2020; 11 (7): 6542-6551.

Serum metabolomics analysis reveals amelioration effects of sea cucumber ether phospholipids on oxidative stress and inflammation in high-fat diet-fed mice., Wang X, Lan H, Sun T, Cong P, Xue C, Xu J., Food Funct. 13 (19): 10134-10146.

Fucoidan from sea cucumber cooking liquid: Structural analysis, physicochemical properties, and anti-Helicobacter pylori potential., Cao J, Qin L, Liu M, Yao M, Wang K, Lin H, Qu C, He Y, Xue C, Miao J., Int J Biol Macromol. February 28, 2025; 141593.

A novel endo-1,3-fucanase in glycoside hydrolase family 187 provided a biotechnological tool for preparing sulfated fucan oligosaccharides., Shen J, Zheng L, Chen G, Khamleng A, Xue C, Chang Y., Int J Biol Macromol. February 16, 2025; 305 (Pt 2): 141171.

Establishment of a workflow for high-throughput identification of anti-inflammatory peptides from sea cucumbers., Jiang B, Liu J, Zhu Z, Fu L, Chang Y, Wang Y, Xue C., Food Res Int. December 29, 2024; 197 (Pt 1): 115171.

Biochemical characterization and cleavage specificities analyses of three endo-1,3-fucanases within glycoside hydrolase family 174., Shen J, Liu G, Chen G, Zhang Y, Mei X, Zheng L, Xue C, Chang Y., Carbohydr Polym. July 1, 2024; 335 122083.

Investigation of the Presence of Fibrillin in Sea Cucumber (Apostichopus japonicus) Body Wall by Utilizing Targeted Proteomics and Visualization Strategies., Shi F, Liu K, Chen G, Chang Y, Xue C., J Agric Food Chem. April 17, 2024; 72 (15): 8798-8804.

Sea Cucumber Plasmalogen Regulates the Lipid Profile in High-Fat Diet Mouse Liver via Lipophagy., Wang Z, Wang X, Liu Y, Wang X, Meng N, Cong P, Song Y, Xu J, Xue C., J Agric Food Chem. April 17, 2024;

Sea cucumber plasmalogen enhance lipophagy to alleviate abnormal lipid accumulation induced by high-fat diet., Wang Z, Liu Y, Wang X, Wang X, Wu Y, Song Y, Xu J, Xue C., Biochim Biophys Acta Mol Cell Biol Lipids. April 10, 2024; 1869 (5): 159495.

Novel peptides from sea cucumber intestines hydrolyzed by neutral protease alleviate exercise-induced fatigue via upregulating the glutaminemediated Ca2+ /Calcineurin signaling pathway in mice., Lu X, Wang M, Yue H, Feng X, Tian Y, Xue C, Zhang T, Wang Y., J Food Sci. March 1, 2024; 89 (3): 1727-1738.

The cross-linking ability of dialdo-galactose in food processing condition., Liu Y, Yu J, Cao H, Xue C, Chen K, Xu Y, Sun X., Food Chem. February 1, 2024; 433 137356.

Establishment of a targeted proteomics method for the quantification of collagen chain: Revealing the chain stoichiometry of heterotypic collagen fibrils in sea cucumber., Shi F, Wang Y, Chang Y, Liu K, Xue C., Food Chem. February 1, 2024; 433 137335.

Preparation of Novel Sea Cucumber Intestinal Peptides to Promote Tibial Fracture Healing in Mice by Inducing Differentiation of Hypertrophic Chondrocytes to the Osteoblast Lineage., Yin H, Yue H, Wang M, Zhang T, Zhao YT, Liu H, Wang J, Zheng H, Xue C., Mol Nutr Food Res. January 1, 2024; 68 (2): e2300344.

Characterization of a novel endo-1,3-fucanase from marine bacterium Wenyingzhuangia fucanilytica reveals the presence of diversity within glycoside hydrolase family 168., Shen J, Chen G, Zhang Y, Mei X, Chang Y, Xue C., Carbohydr Polym. October 15, 2023; 318 121104.

Sulfated fucan could serve as a species marker of sea cucumber with endo-1,3-fucanase as the essential tool., Chen G, Shen J, Zhang Y, Shi F, Mei X, Xue C, Chang Y., Carbohydr Polym. July 15, 2023; 312 120817.

The synergistic effect of sea cucumber saponins and caffeine on preventing obesity in high-fat diet-fed mice by extending the action duration of caffeine., Zhao YC, Li LP, Li XY, Wang CC, Yang JY, Xue CH, Wang YM, Zhang TT., J Sci Food Agric. June 1, 2023; 103 (8): 3950-3960.

Sea Cucumber Phospholipids Regulate Cholesterol Metabolism in High-Fat Diet-Induced ApoE-/- Mice., Yang S, Wang X, Li H, Wang X, Song Y, Cong P, Xu J, Xue C., J Nutr. June 1, 2023; 153 (6): 1762-1770.

Comprehensive Lipid Profile of Eight Echinoderm Species by RPLC-Triple TOF-MS/MS., Hu X, Cong P, Song Y, Wang X, Zhang H, Meng N, Fan X, Xu J, Xue C., J Agric Food Chem. May 31, 2023; 71 (21): 8230-8240.

Novel Peptides from Sea Cucumber Intestinal Enzyme Hydrolysates Promote Osteogenic Differentiation of Bone Mesenchymal Stem Cells via Phosphorylation of PPARγ at Serine 112., Yue H, Leng Z, Bo Y, Tian Y, Yan Z, Xue C, Dong P, Wang J., Mol Nutr Food Res. May 1, 2023; 67 (9): e2200451.

Characterization of an endo-1,3-fucanase from marine bacterium Wenyingzhuangia aestuarii: The first member of a novel glycoside hydrolase family GH174., Liu G, Shen J, Chang Y, Mei X, Chen G, Zhang Y, Xue C., Carbohydr Polym. April 15, 2023; 306 120591.

Oxidized inositol stabilizes rehydrated sea cucumbers against non-enzymatic deterioration., Cao H, Liu D, Zhi L, Liu J, Liu Y, Xu H, Wang D, Xu Y, Xue C, Sun X., Food Chem. March 30, 2023; 405 (Pt B): 134973.

Investigating the loss of major yolk proteins during the processing of sea cucumber (Apostichopus japonicus) using an MRM-based targeted proteomics strategy., Jiang B, Zhang H, Wang J, Wang Y, Du X, Chang Y, Xue C., Food Chem. March 15, 2023; 404 (Pt B): 134670.

Preparation and properties of fucoxanthin-loaded liposomes stabilized by sea cucumber derived cholesterol sulfate instead of cholesterol., Wang Y, Yang J, Wang Y, Chang Y, Xue C, Zhang T., J Biosci Bioeng. February 1, 2023; 135 (2): 160-166.

Sea Cucumber Saponins Derivatives Alleviate Hepatic Lipid Accumulation Effectively in Fatty Acids-Induced HepG2 Cells and Orotic Acid-Induced Rats., Li X, Zeng B, Wen L, Zhao Y, Li Z, Xue C, Zhang T, Wang Y., Mar Drugs. November 10, 2022; 20 (11):

Novel Peptides Derived from Sea Cucumber Intestine Promotes Osteogenesis by Upregulating Integrin-Mediated Transdifferentiation of Growth Plate Chondrocytes to Osteoblasts., Yue H, Tian Y, Feng X, Bo Y, Xue C, Dong P, Wang J., J Agric Food Chem. October 19, 2022; 70 (41): 13212-13222.

A Comparative Study of the Anti-Obesity Effects of Dietary Sea Cucumber Saponins and Energy Restriction in Response to Weight Loss and Weight Regain in Mice., Wen L, Li R, Zhao YC, Yang JY, Li XY, Xue CH, Zhang TT, Wang YM., Mar Drugs. October 1, 2022; 20 (10):

Novel peptides from sea cucumber intestinal hydrolysates promote longitudinal bone growth in adolescent mice through accelerating cell cycle progress by regulating glutamine metabolism., Yue H, Tian Y, Feng X, Bo Y, Leng Z, Dong P, Xue C, Wang J., Food Funct. July 18, 2022; 13 (14): 7730-7739.

Comparative study of holothurin A and echinoside A on inhibiting the high bone turnover via downregulating PI3K/AKT/β-catenin and OPG/RANKL/NF-κB signaling in ovariectomized mice., Yue H, Tian Y, Li Y, Bai X, Wang X, Wang Y, Li Z, Xue C, Wang J., Food Funct. April 20, 2022; 13 (8): 4748-4756.

Hepatoprotective effects of sea cucumber ether-phospholipids against alcohol-induced lipid metabolic dysregulation and oxidative stress in mice., Wang X, Wang Y, Liu Y, Cong P, Xu J, Xue C., Food Funct. March 7, 2022; 13 (5): 2791-2804.

Preparation and Characterization of Astaxanthin-loaded Liposomes Stabilized by Sea Cucumber Sulfated Sterols Instead of Cholesterol., Srihera N, Li Y, Zhang TT, Wang YM, Yanagita T, Waiprib Y, Xue CH., J Oleo Sci. March 2, 2022; 71 (3): 401-410.

Characterization of a sulfated fucan-specific carbohydrate-binding module: A promising tool for investigating sulfated fucans., Mei X, Chang Y, Shen J, Zhang Y, Chen G, Liu Y, Xue C., Carbohydr Polym. February 1, 2022; 277 118748.

Absorption, Pharmacokinetics, Tissue Distribution, and Excretion Profiles of Sea Cucumber-Derived Sulfated Sterols in Mice., Li Y, Wang T, Shi HH, Wang YM, Xue CH, Huang QR, Zhang TT., J Agric Food Chem. January 19, 2022; 70 (2): 480-487.

Utilizing heterologously overexpressed endo-1,3-fucanase to investigate the structure of sulfated fucan from sea cucumber (Holothuria hilla)., Chen G, Yu L, Zhang Y, Chang Y, Liu Y, Shen J, Xue C., Carbohydr Polym. November 15, 2021; 272 118480.

Saponins from the Sea Cucumber Promote the Osteoblast Differentiation in MC3T3-E1 Cells through the Activation of the BMP2/ Smads Pathway., Li Z, Tian Y, Ma H, Wang M, Yan Z, Xue C, Wang J., Curr Pharm Biotechnol. October 6, 2021; 22 (14): 1942-1952.

Lipidomics Approach in High-Fat-Diet-Induced Atherosclerosis Dyslipidemia Hamsters: Alleviation Using Ether-Phospholipids in Sea Urchin., Wang X, Chen Q, Wang X, Cong P, Xu J, Xue C., J Agric Food Chem. August 18, 2021; 69 (32): 9167-9177.

Dietary Supplementation with Exogenous Sea-Cucumber-Derived Ceramides and Glucosylceramides Alleviates Insulin Resistance in High-Fructose-Diet-Fed Rats by Upregulating the IRS/PI3K/Akt Signaling Pathway., Yang JY, Zhang TT, Dong Z, Shi HH, Xu J, Mao XZ, Wang YM, Xue CH., J Agric Food Chem. August 18, 2021; 69 (32): 9178-9187.

Characterizing gangliosides in six sea cucumber species by HILIC-ESI-MS/MS., Wang X, Wang X, Cong P, Zhang X, Zhang H, Xue C, Xu J., Food Chem. August 1, 2021; 352 129379.

Characterization of Gangliosides in Three Sea Urchin Species by HILIC-ESI-MS/MS., Ma Y, Wang X, Wang Z, Cong P, Xu J, Xue C., J Agric Food Chem. July 14, 2021; 69 (27): 7641-7651.

Sterol sulfate alleviates atherosclerosis via mediating hepatic cholesterol metabolism in ApoE-/- mice., Ding L, Xu ZJ, Shi HH, Xue CH, Huang QR, Yanagita T, Wang YM, Zhang TT., Food Funct. June 8, 2021; 12 (11): 4887-4896.

Amino Acid Profiling with Chemometric Analysis as a Feasible Tool for the Discrimination of Marine-Derived Peptide Powders., Wang Q, Wang Y, Jiang X, Ma L, Li Z, Chang Y, Wang Y, Xue C., Foods. June 4, 2021; 10 (6):

Uncovering proteome variations of differently heat-treated sea cucumber (Apostichopus japonicus) by label-free mass spectrometry., Jiang B, Hu L, Zhang X, Zhang H, Zhang F, Chen L, Li Z, Zhao X, Xue C, Jiang X., Food Chem. May 15, 2021; 344 128575.

Sea urchin gangliosides exhibit neuritogenic effects in neuronal PC12 cells via TrkA- and TrkB-related pathways., Wang X, Li Y, Wang Y, Liu Y, Xue C, Cong P, Xu J., Biosci Biotechnol Biochem. February 24, 2021; 85 (3): 675-686.

Structure-function relationship analysis of fucoidan from sea cucumber (Holothuria tubulosa) on ameliorating metabolic inflammation., Zhu Y, Tian Y, Wang N, Chang Y, Xue C, Wang J., J Food Biochem. January 1, 2021; 45 (1): e13500.

Maternal diet with sea urchin gangliosides promotes neurodevelopment of young offspring via enhancing NGF and BDNF expression., Wang X, Cong P, Wang X, Liu Y, Wu L, Li H, Xue C, Xu J., Food Funct. November 18, 2020; 11 (11): 9912-9923.

Functional properties of gonad protein isolates from three species of sea urchin: a comparative study., Shang WH, Yan JN, Du YN, Cui XF, Su SY, Han JR, Xu YS, Xue CF, Zhang TT, Wu HT, Zhu BW., J Food Sci. November 1, 2020; 85 (11): 3679-3689.

Investigation of structural proteins in sea cucumber (Apostichopus japonicus) body wall., Wang Y, Tian M, Chang Y, Xue C, Li Z., Sci Rep. October 30, 2020; 10 (1): 18744.

Sea cucumbers-derived sterol sulfate alleviates insulin resistance and inflammation in high-fat-high-fructose diet-induced obese mice., Zhang HJ, Chen C, Ding L, Shi HH, Wang CC, Xue CH, Zhang TT, Wang YM., Pharmacol Res. October 1, 2020; 160 105191.

Exogenous natural EPA-enriched phosphatidylcholine and phosphatidylethanolamine ameliorate lipid accumulation and insulin resistance via activation of PPARα/γ in mice., Tian Y, Liu Y, Xue C, Wang J, Wang Y, Xu J, Li Z., Food Funct. September 23, 2020; 11 (9): 8248-8258.

Sea Cucumber Sterol Alleviates the Lipid Accumulation in High-Fat-Fructose Diet Fed Mice., Zeng BB, Zhang LY, Chen C, Zhang TT, Xue CH, Yanagita T, Li ZJ, Wang YM., J Agric Food Chem. September 9, 2020; 68 (36): 9707-9717.

Oxidized Oligosaccharides Stabilize Rehydrated Sea Cucumbers against High-Temperature Impact., Liu J, Xu Y, Xia T, Xue C, Liu L, Chang P, Wang D, Sun X., Int J Mol Sci. July 23, 2020; 21 (15):

The exogenous natural phospholipids, EPA-PC and EPA-PE, contribute to ameliorate inflammation and promote macrophage polarization., Tian Y, Liu Y, Xue C, Wang J, Wang Y, Xu J, Li Z., Food Funct. July 1, 2020; 11 (7): 6542-6551.

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