Dr. Charles A. Ettensohn
We are interested in understanding how the process of embryonic development is encoded by the genome. During embryogenesis, one-dimensional information contained in the sequence of nucleotides in genomic DNA is translated into the three-dimensional form of multi-cellular organisms. At the core of development is the selective activation of distinct batteries of genes in different embryonic cells. These genes interact with one another in complex, dynamic networks. Programs of gene activity underlie cell behaviors during development, and cell behaviors, in turn, drive higher-order tissue anatomy. Our goal is to understand this remarkable flow of biological information from DNA sequence into morphology.
Carnegie Mellon University
4400 5th Avenue, 611, Mellon Institute