metalloproteases, matrix metalloproteinase, aminopeptidase N families, chorionic gonadotropin
I currently have two research projects in my laboratory. The main project studies the role of metalloproteases in embryonic development. We are investigating the expression and function of two different groups of metalloproteases in embryonic development of the sea urchin model system. Using data from the Sea Urchin Genome Project, we have been able to identify several genes in the Matrix Metalloproteinase and Aminopeptidase N families. We are currently examining the temporal and spatial expression patterns of these genes and will soon begin to investigate the function of these proteins in embryonic development. The second project in my lab is a study performed in collaboration with researchers at Fox Chase Cancer Center. We are investigating the effects of the hormone human Chorionic Gonadotropin on breast cancer cells. This hormone reduces the growth of breast cancer cells and it alters the gene expression profile of these cells. We are investigating these effects of the hormone to contribute to other studies examining the possibility of using human Chorionic Gonadotropin to treat breast cancer.
Penn State Abington
Web Page: https://abington.psu.edu/person/eric-paul-ingersoll