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Nucleic Acids Res
1991 Nov 25;1922:6249-54. doi: 10.1093/nar/19.22.6249.
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Identification of two homologous mitochondrial DNA sequences, which bind strongly and specifically to a mitochondrial protein of Paracentrotus lividus.
Roberti M
,
Mustich A
,
Gadaleta MN
,
Cantatore P
.
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Using a combination of band shift and DNasel protection experiments, two Paracentrotus lividus mitochondrial sequences, able to bind tightly and selectively to a mitochondrial protein from sea urchin embryos, have been found. The two sequences, which compete with each other for binding to the protein, are located in two genome regions which are thought to contain regulatory signals for mitochondrial replication and transcription. A computer analysis suggests that the sequence TTTTRTANNTCYYATCAYA, common to the two binding regions, is the minimal recognition signal for the binding to the protein. We discuss the hypothesis that the protein binding capacity of these two sequences is involved in the control of sea urchin mtDNA replication during developmental stages.
Albring,
Association of a protein structure of probable membrane derivation with HeLa cell mitochondrial DNA near its origin of replication.
1977, Pubmed
Albring,
Association of a protein structure of probable membrane derivation with HeLa cell mitochondrial DNA near its origin of replication.
1977,
Pubmed
Attardi,
Biogenesis of mitochondria.
1988,
Pubmed
Bogenhagen,
Purification of Xenopus laevis mitochondrial RNA polymerase and identification of a dissociable factor required for specific transcription.
1988,
Pubmed
Bradford,
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.
1976,
Pubmed
Cantatore,
RNA synthesis in isolated mitochondria from sea urchin embryos.
1974,
Pubmed
,
Echinobase
Cantatore,
Organization, structure, and evolution of mammalian mitochondrial genes.
1987,
Pubmed
Cantatore,
Mapping and characterization of Paracentrotus lividus mitochondrial transcripts: multiple and overlapping transcription units.
1990,
Pubmed
,
Echinobase
Cantatore,
The complete nucleotide sequence, gene organization, and genetic code of the mitochondrial genome of Paracentrotus lividus.
1989,
Pubmed
,
Echinobase
Cordonnier,
A DNA binding protein showing sequence specificity for a region containing the replication origin of Xenopus laevis mitochondrial DNA.
1987,
Pubmed
Elliott,
Mutually exclusive synthetic pathways for sea urchin mitochondrial rRNA and mRNA.
1989,
Pubmed
,
Echinobase
Fisher,
A transcription factor required for promoter recognition by human mitochondrial RNA polymerase. Accurate initiation at the heavy- and light-strand promoters dissected and reconstituted in vitro.
1985,
Pubmed
Fisher,
Purification and characterization of human mitochondrial transcription factor 1.
1988,
Pubmed
Fisher,
Flexible recognition of rapidly evolving promoter sequences by mitochondrial transcription factor 1.
1989,
Pubmed
Fried,
Kinetics and mechanism in the reaction of gene regulatory proteins with DNA.
1984,
Pubmed
Jacobs,
Sea urchin egg mitochondrial DNA contains a short displacement loop (D-loop) in the replication origin region.
1989,
Pubmed
,
Echinobase
Matsumoto,
Mitochondrial DNA replication in sea urchin oocytes.
1974,
Pubmed
,
Echinobase
Mignotte,
Characterization of a Xenopus laevis mitochondrial protein with a high affinity for supercoiled DNA.
1986,
Pubmed
Van Tuyle,
The rat liver mitochondrial DNA-protein complex: displaced single strands of replicative intermediates are protein coated.
1985,
Pubmed
Winkley,
A multicomponent mitochondrial RNA polymerase from Saccharomyces cerevisiae.
1985,
Pubmed
